Biometer Industrial Laboratory Handheld Portable Ultrasonic Homogenizer Sonicator Cell ...

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Description:

We can supply sonicator in 20Khz, 28Khz,40Khz, and probe customized.Meet the requirements of each processing capacity, From test tubes, to beakers, to small containers, there is always a probe suits you.

Ultrasonic homogenizers, sometimes referred to by the popular brand names Sonicator or Sonifier, disrupt tissues and cells through cavitation and ultrasonic waves. They consist of three parts:

A generator which provides and controls the power

A transducer (also referred to as a converter) which contains piezoelectric crystals that convert the electric energy to very high-frequency mechanical motion. The converter also amplifies this signal.

A titanium probe or “horn” which rapidly vibrates in a longitudinal direction, transmitting the ultrasonic energy to the sample.

Homogenization occurs both directly through the ultrasonic forces as well as through cavitation - the rapid formation and collapse of bubbles. This combination of forces make ultrasonic homogenizers excellent for cell disruption and particle size reduction.

Parameter:

Benefits & Drawbacks

Ultrasonic homogenizers excel when your sample is mostly liquid or consists of small particles in a liquid and you desire thorough homogenization. These include particle size reduction, cell disruption, creating emulsions, and dispersion of nanoparticles or other small particles. Additionally, certain applications requiring very high energy over a small area, such as DNA shearing, may be performed using an ultrasonic homogenizer.

Ultrasonic homogenizers are unsuitable for applications where your sample is mostly solid and / or not immersed in a liquid buffer. For example, homogenization of large, tough tissue samples is generally only possible if the tissue is macerated prior to processing. Additionally, ultrasonic processing for life science applications where intact cells or organelles are desired.

Ultrasonic homogenization generates a very large amount of heat. For heat-sensitive applications, such as RNA extraction, an ultrasonic homogenizer may not be appropriate. If one is to be used, ensure that you have a way of cooling your sample and use a pulsed homogenization program to allow heat to dissipate between pulses.

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