Applications Of Ultrasonic Atomization Spraying in The Medical Field
Nov 11, 2025
In today's rapidly developing medical technology landscape, ultrasonic spraying technology is gradually emerging, bringing numerous innovative applications to the medical field. This technology utilizes high-frequency ultrasonic energy to transform liquids into uniform micron-sized droplets, thereby achieving high-precision and highly uniform coating preparation. Its unique advantages make it widely applicable in the medical industry, with applications ranging from medical device manufacturing to drug delivery systems.
What are the applications of ultrasonic spraying in the medical field?
◆ Drug-eluting stent coating: The FUNSONIC drug-eluting stent coating machine is equipped with a line-jet ultrasonic nozzle and can be used for drug coating on various stents, including coronary stents and peripheral stents. This equipment can dissolve drugs such as rapamycin and paclitaxel in organic solvents and then uniformly spray them onto the stent surface, forming a uniform, dense, non-adhesive, and free of pinholes and bubbles.

◆ Drug-Eluting Balloon Coating: The RPS-SONIC ultrasonic spraying system is a coating system specifically designed for various balloon catheters, capable of spraying balloons up to 280mm in length. This system can be equipped with a multi-nozzle system and a uniquely designed multi-balloon catheter tooling system, enabling simultaneous spraying of multiple balloons and increasing production speed.
◆ Medical Nonwoven Fabric Coating: Ultrasonic spraying technology can be used to prepare hydrophilic/hydrophobic coatings for medical nonwoven fabrics. For products requiring rapid fluid wicking, such as surgical drapes and inner layers of protective clothing, hydrophilic agents such as polyethylene glycol can be precisely sprayed to achieve controlled liquid diffusion. For materials requiring barrier properties, such as outer layers of protective clothing and surgical drapes, hydrophobic agents such as fluoropolymers can be uniformly applied to form a dense barrier. Furthermore, antibacterial and antiviral agents can be uniformly sprayed onto the surface of nonwoven fabrics to improve their antibacterial properties.

◆ Blood collection tube coating: Ultrasonic spraying systems can be used for coating blood collection tubes, such as spraying silica slurry onto the tube wall to form a uniform silica particle film, accelerating blood clotting. This technology can also uniformly coat anticoagulants such as heparin and EDTA, providing excellent coating uniformity and repeatability. The ultrasonic vibration of the nozzle breaks down any agglomerates, ensuring uniform coating on the tube wall.

◆ Medical Device Lubrication and Anti-Adhesion Coatings: In vascular interventional surgery, ultrasonic spraying technology is used to coat the surfaces of catheters, guidewires, and other instruments with hydrophilic polymers, such as polyacrylamide and polyethylpyrrolidone, forming a hydrated lubricating layer. This reduces the frictional resistance between the instrument and the blood vessel wall by more than 80%, effectively reducing tissue damage and blood flow interference. Clinical data shows that high-quality lubricating coatings can shorten operation time by 25% and reduce the complication rate by 40%.
◆ Medical Device Antibacterial Coatings: Coating the surfaces of cardiac stents and catheters with fluorinated coatings such as PTFE can inhibit thrombus formation, improve blood compatibility, and reduce the risk of postoperative complications. For implants such as artificial joints and orthopedic screws, coating treatment can reduce the release of metal ions and enhance long-term biocompatibility.
