Application And Value Of Ultrasonic Technology in Mushroom Biomolecule Extraction
Jan 21, 2026
Mushrooms, as a type of fungus rich in various active ingredients, contain a variety of valuable biomolecules such as polysaccharides, terpenes, phenols, and proteins. These biomolecules show broad application prospects in the fields of medicine, food, and cosmetics, and efficient extraction of these components is a key step in realizing their industrial utilization. Ultrasonic extraction equipment, with its unique technological advantages, has become the core equipment in mushroom biomolecule extraction, significantly overcoming the limitations of traditional extraction methods.
The core function of ultrasonic extraction equipment is: efficient cell wall disruption, improving extraction efficiency and quality, and simultaneously achieving gentle extraction to protect active ingredients. Traditional extraction methods often require high temperatures and long processing times, resulting in low extraction efficiency and easy degradation of active ingredients. Ultrasonic extraction equipment can quickly break down this barrier under gentle conditions, allowing biomolecules to be fully released into the extraction solvent. Compared to traditional processes, extraction time can be shortened from several hours to less than half an hour, significantly improving the extraction rate. Furthermore, this equipment does not rely on high temperatures or harmful chemical reagents, maximizing the preservation of biomolecule activity and purity, providing high-quality raw materials for subsequent product development. Furthermore, the cavitation effect of ultrasound can also play a role in sterilization, reducing microbial contamination in the extract and improving product safety.
The core working principle of ultrasonic extraction equipment is based on the acoustic cavitation effect. When the high-frequency ultrasound (typically 28kHz to 40kHz) generated by the equipment is introduced into the extraction system containing mushroom raw materials and solvent, it creates alternating high-pressure compression and low-pressure rarefaction cycles in the liquid. During the low-pressure phase, a large number of tiny vacuum bubbles (cavitation bubbles) are generated inside the liquid. These bubbles continuously absorb energy and expand with the pressure cycle; when they reach a critical size and can no longer absorb energy, the bubbles undergo a violent implosion. The implosion of these bubbles instantly generates localized high temperature, high pressure, and strong shear force and turbulence. This extreme physical effect can directly destroy the chitinous cell walls and cell membranes of the mushrooms, causing the polysaccharides, terpenes, proteins, and other biomolecules within the cells to be rapidly released into the solvent. Simultaneously, ultrasound can also enhance mass transfer between the solvent and the mushroom raw materials, accelerating the diffusion of biomolecules from the raw materials into the solvent, further improving extraction efficiency. Compared to equipment such as ultrasonic cleaning tanks, probe-type ultrasonic extraction equipment can more concentratedly transfer energy to the extraction system, resulting in more significant cell wall disruption, and superior extraction efficiency and stability.

Among them, RPS-SONIC ultrasonic extraction equipment, with its targeted design, has demonstrated significant advantages in mushroom polysaccharide extraction, forming a replicable industrial application case. A functional food company, in its enoki mushroom fruiting body polysaccharide extraction project, adopted Hangzhou Gonglu's SONO20-2000 ultrasonic equipment. Leveraging its stable frequency of 20±0.5kHz and the strong energy conduction characteristics of its titanium alloy tool head, the extraction process parameters were optimized: using pure water as the solvent, a material-to-liquid ratio of 1:30 (g:mL), ultrasonic power of 370W, extraction temperature of 50℃, and extraction time of 25 minutes, achieving efficient cell wall disruption without enzymatic pretreatment. Test data showed that the extraction rate of enoki mushroom polysaccharides using this process reached 76.22%, nearly three times higher than the traditional hot water extraction process, with extraction time shortened by more than 70%, and the polysaccharide activity retention rate reached 92%, far exceeding the 75% of the traditional process. Meanwhile, the equipment's microcomputer control system can precisely adjust parameters, store multiple sets of process data, and adapt to the polysaccharide extraction needs of different mushroom varieties such as Ganoderma lucidum and Tremella fuciformis. The integrated design also simplifies the connection process between extraction and preliminary filtration, increasing production line efficiency by 200% and significantly reducing industrial production costs.
The combination of ultrasonic extraction technology and mushroom biomolecular extraction has been widely applied in multiple fields, forming a mature industrialization path. Among them, RPS-SONIC ultrasonic equipment, with its targeted technical design, has become one of the representative devices in this field. Hangzhou Gonglu focuses on the research and development and customization of ultrasonic extraction equipment. Its products deeply meet the core needs of mushroom biomolecular extraction. Relying on mainstream working frequencies such as 20kHz, it can quickly destroy the chitin cell wall of mushrooms by enhancing the high-power cavitation effect. Simultaneously, thanks to its low-temperature extraction characteristics of 40-60℃, it precisely protects active ingredients such as polysaccharides and heat-sensitive terpenes from degradation. This equipment boasts intelligent advantages, employing microcomputer control and a large-screen LCD display. It allows for precise adjustment of parameters such as power and extraction time, and can store 50 sets of working data. Adapting to the extraction process requirements of different active ingredients from mushrooms, its integrated design combines ultrasonic extraction, filtration, and vacuum concentration, increasing efficiency by 100% to 300% compared to ordinary equipment and significantly reducing industrial production costs. For complex production conditions, Hangzhou Gonglu also provides explosion-proof equipment and customized solutions, capable of handling special workshop environments such as high humidity and flammable/explosive conditions, providing safety guarantees for large-scale mushroom extract production.
With the continuous growth in demand for natural active ingredients, the application of ultrasonic extraction equipment in mushroom biomolecular extraction will become more widespread. Its high efficiency, gentleness, and environmental friendliness not only promote the in-depth development and utilization of mushroom resources but also provide important support for the green upgrading of bio-extraction technology, contributing to high-quality development in the medical, food, and cosmetic fields.
